Project Overview

Work flow and interdependencies of the nine work packages

Initially, the IMPROvED programme focuses on developing the clinical study framework (WP01), followed by a large-scale first time mothers to a phase IIa prognostic hospital-based clinical study (WP03). Endeavours to optimise the protein and metabolite screening tests will parallel those of the clinical study; the preferred platforms will be finalised and the biomarker algorithms ‘locked’ (WPs 04 and 05) prior to participant samples becoming available. Subsequent processing of the IMPROvED cohort samples and assessment of the performance of the two tests (WP 06) will be completed after the recruitment ending.